Evidence about the Medtronic IN.PACT Admiral Paclitaxel-eluting PTA Balloon | Which Medical Device
Categorised under:
Interventional Radiology
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Vascular
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Drug Eluting Balloons
Interventional Radiology
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Vascular
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Infrapopliteal arterial disease management
The authors aimed to validate a novel iliofemoral in-stent restenosis (ISR) model for the efficacy evaluation of paclitaxel-coated balloons (PCB) using the familial hypercholesterolemic swine (FHS).
They concluded:
The FHS model of iliofemoral ISR demonstrated a dose-dependent effect on the inhibition of neointimal proliferation of a clinically validated PCB technology. This model represents a positive step toward the efficacy evaluation of PCB in the peripheral vascular territory.
Credits: PubMed, JACC Cardiovasc Interv. 2012 Oct;5(10):1081-8
Review of clinical data with Paccocath- coated balloon catheters.
In this review we first outline the development of Paccocath? balloons to then provide an overview of the clinical results obtained with the modified coating. Furthermore we examine possible mechanism of action by which single administration of an antiproliferative drug dose using paclitaxel-coated balloons inhibits restenosis
Credits: PubMed, Review of clinical data with Paccocath- coated balloon catheters.
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