Thrombin injection splenic artery pseudoaneurysm - 13 November 2008

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This video demonstrates the use of thrombin in the percutaneous treatment of a narrow necked splenic artery pseudoaneurysm:

The thrombin component of Tisseel was used.

The first reported cases of thrombin injection for aneurysms and pseudoaneurysms were in 1986: 

Cope C, Zeit R.  Coagulation of Aneurysms by Direct Percutaneous Thrombin Injection.  AJR 1986;147:383-7. 

Since then we reported our experience using percutaneous thrombin injection with and without balloon occlusion of the parent vessel: 

Loose HW,.Haslam PJ. The management of peripheral arterial aneurysms using percutaneous injection of fibrin adhesive. Br.J.Radiol. 1998;71:1255-9. (13 cases balloon)

Owen RJ, Haslam PJ, Elliott ST, Rose JD, Loose HW. Percutaneous ablation of peripheral pseudoaneurysms using thrombin: a simple and effective solution. Cardiovasc.Intervent.Radiol. 2000;23:441-6. (25 cases, 19 with balloon) 

The technique has become widely established in the treatment of pseudoaneurysms.  

Dr Phil Haslam Consultant Interventional Radiologist

Dr Rob Williams Consultant Interventional Radiologist

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